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WebMar 8, 2024 · Most published information on drug elimination in renal failure is usually stated in terms of CrCl using the Cockcroft & Gault equation. The BNF is a notable exception having adopted eGFR for most drugs. WebDec 11, 2024 · Hepatic dysfunction, renal parenchymal infection, severe dehydration, metabolic acidosis, severe renal failure (creatinine clearance or GFR<10 ml/min.) or gout. Hiprex may be used where mild (20-50 ml/min.) to moderate (10-20 ml/min.) renal insufficiency is present. dni ruc sunat
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