WebJul 15, 2024 · Spotlight Therapeutics. Jul 2024 - Present9 months. Hayward, California, United States. Express Cas9 variants in E. coli and …
Scientist ll, Purification - LinkedIn
WebA chimera is a single organism containing two populations of genetically distinct cells originating from two different zygotes. Chimerism has now been extensively described in … WebAdditional chimeric proteins used for therapeutic applications include: Aflibercept: A human recombinant protein that aids in the treatment of oxaliplatin-resistant metastatic … guy in jail
About - Kymera Therapeutics
WebIn this review, we summarize recent advances in developing aptamer-mediated siRNA delivery systems for RNAi therapeutics, mainly aptamer-siRNA chimeras and aptamer-functionalized nanocarriers incorporating siRNA, with a focus on their molecular designs and formulations. In addition, the challenges and engineering strategies of aptamer-mediated ... WebOct 10, 2024 · Aptamer-siRNA chimeras (AsiCs), composed by an aptamer and a siRNA or a Dicer substrate siRNA (DsiRNA), bind through the aptamer to a target molecule on the cell surface (e.g., cell receptor, integrin, adhesion molecules), are internalized through endocytosis, and achieve specific delivery. WebWe are pioneering novel small-molecule therapeutic candidates, called GeneTAC™ molecules (Gene Targeted Chimera), designed to be disease-modifying and to target the underlying cause of inherited nucleotide repeat expansion diseases. GeneTAC™ Platform. guyitt house palmyra