WebMerCreMerはエストロゲン受容体のリガンド結合ドメインとCreリコンビナーゼとの融合タンパク 通常は細胞質に存在し、リガンドである タモキシフェン の投与により核内に … Web18 dec. 2024 · During the past two decades, experiments utilizing constitutive as well as tamoxifen-activated Myh6-driven Cre recombinase transgenes have driven remarkable …
Comparison of the Tamoxifen Regulated Chimeric Cre …
Web1 mei 2024 · As shown in Fig. 1, we developed a myofiber-specific inducible CreER transgenic mouse in which the HSA promoter was used to drive expression of CreER.We used a modified version of CreER, which contained mutated ERs (Mer) on both ends of the Cre protein. We chose to use this inducible version of Cre, referred to as MerCreMer … http://www.cqwestern.net/exper-i977.html recommandation cnam r457
心脏特异 Cre 转基因小鼠-
Web5 jan. 2024 · The Cre-LoxP technology, including the tamoxifen (TAM) inducible MerCreMer (MCM), is increasingly used to delineate gene function, understand the … Web条件性基因敲除小鼠. 首先，在待敲除的一段目标DNA序列的两端各放置一个Loxp序列，得到flox小鼠。. 然后，将flox小鼠与带有组织特异性表达Cre的小鼠交配繁殖，以获得在特定 … WebPlasmid KA1153_pPBCAG-MerCreMer-IN from Dr. Hans Schöler's lab contains the insert MerCreMer-IRES-Neo and is published in Cell Stem Cell. 2024 Aug 2;23(2):266-275.e6. doi: 10.1016/j.stem.2024.05.020. Epub 2024 Jun 14. This plasmid is … recommandation cancer thyroïde 2020