Siglec 10 antibody
WebExpression of SIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use … WebIn one embodiment, an anti-Siglec-9 antibody has a KD of about 1×10 −7 M to about 1×10 −10 M, about 1×10 −8 M to about 1×10 −10 M, or about 1×10 −9 M to about 1×10 −11 M, …
Siglec 10 antibody
Did you know?
WebWe offer Siglec-10 Antibodies for use in common research applications: Blockade of Receptor-ligand Interaction, ELISA, Flow Cytometry, Immunohistochemistry, … WebSiglec-G is the apparent ortholog of human Siglec-10 (4). The human Siglec-10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a 534 aa …
WebIn cancer it is important to consider the mode of action of CD24-Fc. The binding to Siglec-10 on immune effector cells as an agonist could render cells more immunosuppressive. In … WebSIGLEC10 antibody LS-C325111 is an unconjugated rabbit polyclonal antibody to human SIGLEC10 (aa667-695). Validated for ELISA and WB. Products. Research Areas. COVID-19. Resources. ... SIGLEC10 SIGLEC-10 Siglec-like gene 2 Siglec-like protein 2 PRO940 SLG2. See All SIGLEC10 Antibodies. Host. Rabbit.
WebSiglec-15, which selectively drives immunosuppression in the tumor microenvironment, has emerged as a viable therapeutic target. In a phase I trial of NC318, a Siglec-15 antibody, … WebHigh-quality Siglec-10 proteins from ACROBiosystems. Various species and tags of Siglec-10 proteins. Minimal Batch-to-Batch Variation. Bulks in stock. Login Register. Bulk order. Clear ... Antibodies Anti-idiotypic antibody Anti-FMC63 mAb …
Websialic acid binding Ig like lectin 10 , PRO940 , SIGLEC-10 , SLG2 ... WB analysis of OVCAR-3 cells using GTX45910 SIGLEC10 antibody at 0.2-1μg/ml. REFERENCE. There are currently …
WebRabbit Polyclonal Anti-SIGLEC10 Antibody against Human sialic acid binding Ig-like lectin 10. Antibody validation: Validated for Immunohistochemistry and Western Blot. Support; … north face backpack tillysWebNov 29, 2024 · The anti-Siglec-10 (clone 5G6) was used as a blocking antibody to inhibit the CD24-Siglec-10 axis, and robustly improved the phagocytosis of tumour cells by … north face backpacks shotgunWebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane protein that has four extracellular Ig-like domains, a transmembrane region, and a cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (2). north face backpacks whiteLike most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more north face backpacks store locatorWebSIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are … how to save bash script in windowsWebSIGLEC10 antibody LS-C187565 is an unconjugated mouse monoclonal antibody to human SIGLEC10. Validated for Flow. Products. Research Areas. COVID-19. Resources. ... (NK) cells. Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic ... how to save baseballWebBuy rabbit polyclonal antibody to SIGLEC10 (A54002). Applications: ELISA, IP and WB. Reactivity: Human and Rat. ️ Low Prices ️ 100% Guarantee. Useful Links. 01223 298 ... north face backpack washing instructions